Zoes
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Email security for Microsoft 365

What Exchange Online Protection and Defender for Office 365 cover, the settings worth changing, what still gets through, and how an API-based layer fits in.
By · October 14, 2026 · 5 min read
A team gathered around a laptop in an open office
Photo: Vitaly Gariev on Unsplash

What Microsoft includes

Layer
Included with
Covers
Exchange Online Protection
Every Exchange Online plan
Spam, bulk mail, known malware, spoofing checks
Defender for Office 365 Plan 1
Business Premium, or $2/user/month
Safe Links, Safe Attachments, impersonation protection
Defender for Office 365 Plan 2
E5, or $5/user/month
Plan 1 plus Threat Explorer, automated investigation, attack simulation

Prices are Microsoft list prices at the time of writing.

Settings worth changing

Setting
Where
Why
Require MFA
Entra admin center → Security defaults or Conditional Access
A phished password alone no longer opens the mailbox
Preset security policies
Defender portal → Email & collaboration → Policies & rules → Threat policies
Applies Microsoft's recommended Standard or Strict settings in one step
Block external auto-forwarding
Defender portal → Anti-spam policies → outbound policy
Stops a compromised mailbox quietly copying mail outside
DKIM signing
Defender portal → Email authentication settings
Needed for DMARC on your own domain
Review enterprise apps
Entra admin center → Enterprise applications
See which apps can read mail, and remove what you do not use

What still gets through

Impersonation protection in Defender works best once it is configured with the users and domains to protect. Without that tuning - and without Defender at all on Business Basic or Standard - targeted, low-volume mail still reaches inboxes:

  • A supplier lookalike asking for an invoice to be paid to new details.
  • A "from the CEO" request for a fast transfer, with no link or attachment.
  • A login page on a domain registered this week, sent to one person.
  • Mail from a real, compromised partner account.

The last one has its own post: vendor email compromise.

Adding Zoes to Microsoft 365

Zoes connects as an enterprise app through the Microsoft Graph API. It reads mail after Exchange Online Protection and Defender have run, so it does not conflict with either.

  1. 1Sign in to Zoes with a Microsoft work account.
  2. 2A Global Administrator approves the admin-consent screen once for the tenant.
  3. 3Choose which users to protect from the synced directory.
Zoes verdict
What happens in Outlook
Dangerous
Tagged Dangerous and moved to a Dangerous folder
Suspicious
Tagged Suspicious and moved to a Suspicious folder
Spam
Moved to Junk Email
Graymail
Moved to the Other tab of Focused Inbox
Likely safe, Unknown
Left where it is

Revoke access at any time by removing the Zoes enterprise app in the Entra admin center. For a side by side, see Zoes vs. Defender for Office 365.

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